I encounted “Outlook data file cannot be accessed” error today

Scenario: Win 11 Pro, MS Office Outlook 365, “Outlook data file cannot be accessed” error when open MS Outlook.

What I tried but fail:

  1. ScanPST
  2. Copy PST file to other location (to D drive)
  3. Check PST file permmission

Finally , it is fixed by create a new MS Outlook profile but use the same PST file.